• Mouse HTT (Huntingtin) Sandwich ELISA Kit (STJE0009608)

Mouse HTT (Huntingtin) Sandwich ELISA Kit (STJE0009608)

SKU:
STJE0009608

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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.055ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This HTT Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: HttUniprot ID=HD_MOUSE"
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity The highest level is seen throughout the brain, but it is also found in the stomach, heart, testis, adipose tissue, muscle, spleen, liver, and kidney.
Post Translational Modifications Phosphorylation at Ser-1159 and Ser-1179 by CDK5 in response to DNA damage in nuclei of neurons protects neurons against polyglutamine expansion as well as DNA damage mediated toxicity. Huntingtin: Cleaved by caspases downstream of the polyglutamine stretch. Huntingtin, myristoylated N-terminal fragment: Myristoylated at Gly-530, following proteolytic cleavage at Asp-529.
Function Huntingtin: May play a role in microtubule-mediated transport or vesicle function. Huntingtin, myristoylated N-terminal fragment: Promotes the formation of autophagic vesicles.
Protein Name Huntingtin
Huntington Disease Protein Homolog
Hd Protein Homolog Cleaved Into - Huntingtin - Myristoylated N-Terminal Fragment
Database Links
Cellular Localisation Huntingtin: Cytoplasm
Nucleus
Shuttles Between Cytoplasm And Nucleus In A Ran Gtpase-Independent Manner
Huntingtin
Myristoylated N-Terminal Fragment: Cytoplasmic Vesicle
Autophagosome
Alternative ELISA Names Huntingtin ELISA kit
Huntington Disease Protein Homolog ELISA kit
Hd Protein Homolog Cleaved Into - Huntingtin - Myristoylated N-Terminal Fragment ELISA kit
Htt ELISA kit
Hd ELISA kit
Hdh ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance