• Mouse HSP10 (Heat Shock 10kDa Protein 1) Sandwich ELISA Kit (STJE0009540)

Mouse HSP10 (Heat Shock 10kDa Protein 1) Sandwich ELISA Kit (STJE0009540)

SKU:
STJE0009540

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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.65ng/mL
Detection Limit: 1.56-100ng/mL
Short Description: This HSP10 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Hspe1
Gene ID: 15528
Uniprot ID: CH10_MOUSE
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Co-chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp60, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein.
Protein Name 10 Kda Heat Shock Protein - Mitochondrial
Hsp10
10 Kda Chaperonin
Chaperonin 10
Cpn10
Database Links Reactome: R-MMU-9013408
Cellular Localisation Mitochondrion Matrix
Alternative ELISA Names 10 Kda Heat Shock Protein - Mitochondrial ELISA kit
Hsp10 ELISA kit
10 Kda Chaperonin ELISA kit
Chaperonin 10 ELISA kit
Cpn10 ELISA kit
Hspe1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance