Applications: |
ELISA |
Reactivity: |
Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.051ng/mL |
Detection Limit: |
0.156-10ng/mL |
Short Description: |
This HEXa Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
4.5 hrs |
Gene Symbol: |
Hexa |
Gene ID: |
15211 |
Uniprot ID: |
HEXA_MOUSE |
Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
Tissue Specificity | Ubiquitous. Most abundant in testis, adrenal, epididymis and heart. Low levels seen in the liver. |
Post Translational Modifications | |
Function | Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides. The isozyme S is as active as the isozyme A on the anionic bis-sulfated glycans, the chondroitin-6-sulfate trisaccharide (C6S-3), and the dermatan sulfate pentasaccharide, and the sulfated glycosphingolipid SM2. The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide. Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A. |
Protein Name | Beta-Hexosaminidase Subunit AlphaBeta-N-Acetylhexosaminidase Subunit AlphaHexosaminidase Subunit AN-Acetyl-Beta-Glucosaminidase Subunit Alpha |
Database Links | Reactome: R-MMU-1660662Reactome: -MMU-2022857Reactome: -MMU-2024101Reactome: -MMU-2160916 |
Cellular Localisation | Lysosome |
Alternative ELISA Names | Beta-Hexosaminidase Subunit Alpha ELISA kitBeta-N-Acetylhexosaminidase Subunit Alpha ELISA kitHexosaminidase Subunit A ELISA kitN-Acetyl-Beta-Glucosaminidase Subunit Alpha ELISA kitHexa ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance