• Mouse HCAM (Homing Associated Cell Adhesion Molecule) Sandwich ELISA Kit Ready-To-Use (STJE0015784)

Mouse HCAM (Homing Associated Cell Adhesion Molecule) Sandwich ELISA Kit Ready-To-Use (STJE0015784)

SKU:
STJE0015784

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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 29pg/mL
Detection Limit: 78.1-5000pg/mL
Short Description: This HCAM Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Cd44
Gene ID: 12505
Uniprot ID: CD44_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Expressed in the intestinal epithelium.
Post Translational Modifications N-glycosylated. O-glycosylated.contains chondroitin sulfate glycans which can be more or less sulfated. Phosphorylated.activation of PKC results in the dephosphorylation of Ser-742 (constitutive phosphorylation site), and the phosphorylation of Ser-708.
Function Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection. Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases. Such effectors include PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases and phospholipase C that coordinate signaling pathways promoting calcium mobilization and actin-mediated cytoskeleton reorganization essential for cell migration and adhesion.
Protein Name Cd44 Antigen
Extracellular Matrix Receptor Iii
Ecmr-Iii
Gp90 Lymphocyte Homing/Adhesion Receptor
Hutch-I
Hermes Antigen
Hyaluronate Receptor
Lymphocyte Antigen 24
Ly-24
Phagocytic Glycoprotein 1
Pgp-1
Phagocytic Glycoprotein I
Pgp-I
Cd Antigen Cd44
Database Links Reactome: R-MMU-1474228
Reactome: -MMU-202733
Reactome: -MMU-216083
Reactome: -MMU-2160916
Reactome: -MMU-6798695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Projection
Microvillus
Secreted
Colocalizes With Actin In Membrane Protrusionfs At Wounding Edges
Co-Localizes With Rdx
Ezr And Msn In Microvilli
Alternative ELISA Names Cd44 Antigen ELISA kit
Extracellular Matrix Receptor Iii ELISA kit
Ecmr-Iii ELISA kit
Gp90 Lymphocyte Homing/Adhesion Receptor ELISA kit
Hutch-I ELISA kit
Hermes Antigen ELISA kit
Hyaluronate Receptor ELISA kit
Lymphocyte Antigen 24 ELISA kit
Ly-24 ELISA kit
Phagocytic Glycoprotein 1 ELISA kit
Pgp-1 ELISA kit
Phagocytic Glycoprotein I ELISA kit
Pgp-I ELISA kit
Cd Antigen Cd44 ELISA kit
Cd44 ELISA kit
Ly-24 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance