• Mouse GRIN2A (Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A) Sandwich ELISA Kit (STJE0009303)

Mouse GRIN2A (Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A) Sandwich ELISA Kit (STJE0009303)

SKU:
STJE0009303

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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.045ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This GRIN2A Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Grin2a
Gene ID: 14811
Uniprot ID: NMDE1_MOUSE
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Detected in striatum. Detected in forbrain. Detected in cerebellum (at protein level). Detected in brain cortex, piriform cortex, hippocampus, caudate-putamen, dentate gyrus and granule cell layer.
Post Translational Modifications
Function Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition.channels containing GRIN1 and GRIN2A have lower sensitivity to glutamate and faster deactivation kinetics than channels formed by GRIN1 and GRIN2B. Contributes to the slow phase of excitatory postsynaptic current, long-term synaptic potentiation, and learning.
Protein Name Glutamate Receptor Ionotropic - Nmda 2a
Glun2a
Glutamate Nmda Receptor Subunit Epsilon-1
N-Methyl D-Aspartate Receptor Subtype 2a
Nmdar2a
Nr2a
Database Links Reactome: R-MMU-438066
Reactome: -MMU-8849932
Reactome: -MMU-9609736
Cellular Localisation Cell Projection
Dendritic Spine
Cell Membrane
Multi-Pass Membrane Protein
Synapse
Postsynaptic Cell Membrane
Cytoplasmic Vesicle Membrane
Expression At The Dendrite Cell Membrane And At Synapses Is Regulated By Sorcs2 And The Retromer Complex
Alternative ELISA Names Glutamate Receptor Ionotropic - Nmda 2a ELISA kit
Glun2a ELISA kit
Glutamate Nmda Receptor Subunit Epsilon-1 ELISA kit
N-Methyl D-Aspartate Receptor Subtype 2a ELISA kit
Nmdar2a ELISA kit
Nr2a ELISA kit
Grin2a ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance