Mouse EZH1 (Enhancer Of Zeste Homolog 1) Sandwich ELISA Kit Kit (STJE0008723)

Mouse EZH1 (Enhancer Of Zeste Homolog 1) Sandwich ELISA Kit Kit (STJE0008723)

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STJE0008723
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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.061ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This EZH1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Ezh1
Gene ID: 14055
Uniprot ID: EZH1_MOUSE
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Expressed at high levels in kidney, adrenal gland, testis and brain.
Post Translational Modifications
Function Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
Protein Name Histone-Lysine N-Methyltransferase Ezh1
Enx-2
Enhancer Of Zeste Homolog 1
Database Links
Cellular Localisation Nucleus
Colocalizes With Trimethylated 'Lys-27' Of Histone H3
Alternative ELISA Names Histone-Lysine N-Methyltransferase Ezh1 ELISA kit
Enx-2 ELISA kit
Enhancer Of Zeste Homolog 1 ELISA kit
Ezh1 ELISA kit
Enx2 ELISA kit
output

Information sourced from Uniprot.org

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