• Mouse ErbB3 (V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3) Sandwich ELISA Kit (STJE0008690)

Mouse ErbB3 (V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3) Sandwich ELISA Kit (STJE0008690)

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STJE0008690

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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 34pg/mL
Detection Limit: 78.1-5000pg/mL
Short Description: This ErbB3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Erbb3
Gene ID: 13867
Uniprot ID: ERBB3_MOUSE
Sample Type: serum, plasma or other biological fluids.
Tissue Specificity In the muscle, expression localizes to the synaptic sites of muscle fibers.
Post Translational Modifications Autophosphorylated. Ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase.
Function Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it.ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation.
Protein Name Receptor Tyrosine-Protein Kinase Erbb-3
Glial Growth Factor Receptor
Proto-Oncogene-Like Protein C-Erbb-3
Database Links Reactome: R-MMU-1227986
Reactome: -MMU-1236394
Reactome: -MMU-1250196
Reactome: -MMU-1257604
Reactome: -MMU-1306955
Reactome: -MMU-1358803
Reactome: -MMU-1963642
Reactome: -MMU-5673001
Reactome: -MMU-6785631
Reactome: -MMU-6811558
Reactome: -MMU-8847993
Reactome: -MMU-8863795
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative ELISA Names Receptor Tyrosine-Protein Kinase Erbb-3 ELISA kit
Glial Growth Factor Receptor ELISA kit
Proto-Oncogene-Like Protein C-Erbb-3 ELISA kit
Erbb3 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance