| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.125ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This DKK1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Dkk1 |
| Gene ID: |
13380 |
| Uniprot ID: |
DKK1_MOUSE |
| Sample Type: |
serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity. Plays a role in limb development.attenuates Wnt signaling in the developing limb to allow normal limb patterning. |
| Protein Name | Dickkopf-Related Protein 1Dickkopf-1Dkk-1Mdkk-1 |
| Database Links | Reactome: R-MMU-3772470 |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Dickkopf-Related Protein 1 ELISA kitDickkopf-1 ELISA kitDkk-1 ELISA kitMdkk-1 ELISA kitDkk1 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
