| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
5.4pg/mL |
| Detection Limit: |
15.6-1000pg/mL |
| Short Description: |
This CYR61 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Ccn1 |
| Gene ID: |
16007 |
| Uniprot ID: |
CCN1_MOUSE |
| Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Low in kidney, adrenal gland, testes, brain, and ovary, moderate in heart, uterus, and skeletal muscle, highest in lung. |
| Post Translational Modifications | |
| Function | Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CCN1-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-1/beta-5 and cell proliferation through integrin alpha-v/beta-3. |
| Protein Name | Ccn Family Member 13ch61Cellular Communication Network Factor 1Cysteine-Rich Angiogenic Inducer 61Insulin-Like Growth Factor-Binding Protein 10Ibp-10Igf-Binding Protein 10Igfbp-10Protein Cyr61 |
| Database Links | Reactome: R-MMU-381426Reactome: -MMU-8957275 |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Ccn Family Member 1 ELISA kit3ch61 ELISA kitCellular Communication Network Factor 1 ELISA kitCysteine-Rich Angiogenic Inducer 61 ELISA kitInsulin-Like Growth Factor-Binding Protein 10 ELISA kitIbp-10 ELISA kitIgf-Binding Protein 10 ELISA kitIgfbp-10 ELISA kitProtein Cyr61 ELISA kitCcn1 ELISA kitCyr61 ELISA kitIgfbp10 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
