| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.137ng/mL |
| Detection Limit: | 0.312-20ng/mL |
| Short Description: | This COL1a1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
| Gene Symbol: | Col1a1 |
| Gene ID: | 12842 |
| Uniprot ID: | CO1A1_MOUSE |
| Sample Type: | serum, plasma or other biological fluids. |
| Tissue Specificity | Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite. |
| Post Translational Modifications | Contains mostly 4-hydroxyproline. Proline residues at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. Contains 3-hydroxyproline at a few sites. This modification occurs on the first proline residue in the sequence motif Gly-Pro-Hyp, where Hyp is 4-hydroxyproline. Lysine residues at the third position of the tripeptide repeating unit (G-X-Y) are 5-hydroxylated in some or all of the chains. O-glycosylated on hydroxylated lysine residues. The O-linked glycan consists of a Glc-Gal disaccharide. |
| Function | Type I collagen is a member of group I collagen (fibrillar forming collagen). |
| Protein Name | Collagen Alpha-1(I ChainAlpha-1 Type I Collagen |
| Database Links | Reactome: R-MMU-114604Reactome: -MMU-1442490Reactome: -MMU-1474244Reactome: -MMU-1650814Reactome: -MMU-198933Reactome: -MMU-2022090Reactome: -MMU-202733Reactome: -MMU-216083Reactome: -MMU-2243919Reactome: -MMU-3000171Reactome: -MMU-3000178Reactome: -MMU-430116Reactome: -MMU-75892Reactome: -MMU-76009Reactome: -MMU-8874081Reactome: -MMU-8948216 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative ELISA Names | Collagen Alpha-1(I Chain ELISA kitAlpha-1 Type I Collagen ELISA kitCol1a1 ELISA kitCola1 ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
