| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.053ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This CES1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
Ces1 |
| Gene ID: |
12623 |
| Uniprot ID: |
EST1_MOUSE |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Detected in kidney, liver and lung. |
| Post Translational Modifications | |
| Function | Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate. Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes of 2-arachidonoylglycerol and prostaglandins. Hydrolyzes cellular cholesteryl esters to free cholesterols and promotes reverse cholesterol transport (RCT) by facilitating both the initial and final steps in the process. First of all, allows free cholesterol efflux from macrophages to extracellular cholesterol acceptors and secondly, releases free cholesterol from lipoprotein-delivered cholesteryl esters in the liver for bile acid synthesis or direct secretion into the bile. |
| Protein Name | Liver Carboxylesterase 1Acyl-Coenzyme A -Cholesterol AcyltransferaseCarboxylesterase 1gCholesteryl Ester HydrolaseCehEs-X |
| Database Links | |
| Cellular Localisation | Endoplasmic Reticulum LumenCytoplasmLipid DropletMoves From Cytoplasm To Lipid Droplets Upon Lipid LoadingAssociates With Lipid Droplets Independently Of Triglycerides (Tg) Content Of The Droplets And Hydrolyzes Cholesteryl Esters More Efficiently From Mixed Droplets |
| Alternative ELISA Names | Liver Carboxylesterase 1 ELISA kitAcyl-Coenzyme A -Cholesterol Acyltransferase ELISA kitCarboxylesterase 1g ELISA kitCholesteryl Ester Hydrolase ELISA kitCeh ELISA kitEs-X ELISA kitCes1 ELISA kitCes1g ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
