Mouse CD70/TNFSF7/CD27 Ligand protein (Recombinant) (N-his) (STJP002007)

SKU:
STJP002007

Current Stock:
Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: <0.1 EU/Mu g of the protein by LAL method.
Gene Symbol: Cd70
Gene ID: 21948
Uniprot ID: CD70_MOUSE
Immunogen Region: Glu53-Arg195
Immunogen: Recombinant Mouse CD70/TNFSF7/CD27 Ligand Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu53-Arg195) of Mouse CD70/TNFSF7/CD27 Ligand (Accession #NP_035747.1) fused with a His tag at the N-term
Immunogen Sequence: EHPEPHTAELQLNLTVPRKD PTLRWGAGPALGRSFTHGPE LEEGHLRIHQDGLYRLHIQV TLANCSSPGSTLQHRATLAV GICSPAAHGISLLRGRFGQD CTVALQR
Post Translational Modifications N-glycosylated.
Function Expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells. The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells.
Protein Name Cd70 Antigen
Cd27 Ligand
Cd27-L
Tumor Necrosis Factor Ligand Superfamily Member 7
Cd Antigen Cd70
Database Links Reactome: R-MMU-5669034
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Protein Names Cd70 Antigen protein
Cd27 Ligand protein
Cd27-L protein
Tumor Necrosis Factor Ligand Superfamily Member 7 protein
Cd Antigen Cd70 protein
Cd70 protein
Cd27l protein
Cd27lg protein
Tnfsf7 protein

Information sourced from Uniprot.org

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