| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.121ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This CACNa1E Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Cacna1eUniprot ID=CAC1E_MOUSE" |
| Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Expressed in neuronal tissues, retina, spleen, and pancreatic islet cells. |
| Post Translational Modifications | |
| Function | Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel. They are however insensitive to dihydropyridines (DHP). Calcium channels containing alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing. |
| Protein Name | Voltage-Dependent R-Type Calcium Channel Subunit Alpha-1eBrain Calcium Channel IiBiiCalcium Channel - L Type - Alpha-1 Polypeptide - Isoform 6Voltage-Gated Calcium Channel Subunit Alpha Cav2.3 |
| Database Links | |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Voltage-Dependent R-Type Calcium Channel Subunit Alpha-1e ELISA kitBrain Calcium Channel Ii ELISA kitBii ELISA kitCalcium Channel - L Type - Alpha-1 Polypeptide - Isoform 6 ELISA kitVoltage-Gated Calcium Channel Subunit Alpha Cav2.3 ELISA kitCacna1e ELISA kitCach6 ELISA kitCacnl1a6 ELISA kitCchra1 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
