Applications: |
ELISA |
Reactivity: |
Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
1.45pg/mL |
Detection Limit: |
3.12-200pg/mL |
Short Description: |
This APOA5 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
3 hrs |
Gene Symbol: |
Apoa5 |
Gene ID: |
66113 |
Uniprot ID: |
APOA5_MOUSE |
Immunogen Region: |
Ready-To-Use |
Sample Type: |
serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Tissue Specificity | Liver. |
Post Translational Modifications | Phosphorylated by FAM20C in the extracellular medium. |
Function | Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages. Binds heparin. |
Protein Name | Apolipoprotein A-VApo-AvApoa-VApolipoprotein A5Regeneration-Associated Protein 3 |
Database Links | Reactome: R-MMU-381426Reactome: -MMU-8957275Reactome: -MMU-8963901 |
Cellular Localisation | SecretedEarly EndosomeLate EndosomeGolgi ApparatusTrans-Golgi NetworkIn The Presence Of Sorl1Internalized To Early EndosomesSorted In A Retrograde Fashion To Late EndosomesFrom Which A Portion Is Sent To Lysosomes And DegradationAnother Portion Is Sorted To The Trans-Golgi Network |
Alternative ELISA Names | Apolipoprotein A-V ELISA kitApo-Av ELISA kitApoa-V ELISA kitApolipoprotein A5 ELISA kitRegeneration-Associated Protein 3 ELISA kitApoa5 ELISA kitRap3 ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance