| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.059ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This ADRb1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Adrb1 |
| Gene ID: |
11554 |
| Uniprot ID: |
ADRB1_MOUSE |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | In brain, expressed by glutamatergic and GABAergic neurons of the dorsal pons (at protein level). |
| Post Translational Modifications | Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase. |
| Function | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling. Involved in the regulation of sleep/wake behaviors. |
| Protein Name | Beta-1 Adrenergic ReceptorBeta-1 AdrenoreceptorBeta-1 Adrenoceptor |
| Database Links | Reactome: R-MMU-390696Reactome: -MMU-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEarly EndosomeColocalizes With Rapgef2 At The Plasma MembraneFound In The Golgi Upon Gopc Overexpression |
| Alternative ELISA Names | Beta-1 Adrenergic Receptor ELISA kitBeta-1 Adrenoreceptor ELISA kitBeta-1 Adrenoceptor ELISA kitAdrb1 ELISA kitAdrb1r ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
