JTB Positive Control for STJ505928 peptide (STJ505717)

SKU:
STJ505717-5

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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: JTB Positive Control for STJ505928 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: JTB
Gene ID: 10899
Uniprot ID: JTB_HUMAN
Specificity: This is positive control is recommended for use in combination with JTB antibody STJ505928.
Immunogen: Purified Jumping Translocation Breakpoint protein.
Function Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1. Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.
Peptide Name Protein Jtb
Jumping Translocation Breakpoint Protein
Prostate Androgen-Regulated Protein
Par Protein
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Mitochondrion
Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Spindle
Detected At The Centrosome And Along Spindle Fibers During Prophase And Metaphase
Detected At The Midbody During Telophase
Alternative Peptide Names Protein Jtb protein
Jumping Translocation Breakpoint Protein protein
Prostate Androgen-Regulated Protein protein
Par Protein protein
JTB protein
HSPC222 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance