| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
IQSEC3 Positive Control for STJ501486 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: |
WB: 1:500 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
IQSEC3 |
| Gene ID: |
440073 |
| Uniprot ID: |
IQEC3_HUMAN |
| Specificity: |
This is positive control is recommended for use in combination with IQSEC3 antibody STJ501486. |
| Tissue Specificity | Expressed specifically in the adult brain, predominantly in the cerebral cortex and the olfactory bulb, but not in the fetal brain. Expressed only in mature neurons, but not in undifferentiated neural stem precursor cells (NSPCs), nor in glioma cells. |
| Function | Acts as a guanine nucleotide exchange factor (GEF) for ARF1. |
| Peptide Name | Iq Motif And Sec7 Domain-Containing Protein 3 |
| Database Links | Reactome: R-HSA-9768919 |
| Cellular Localisation | CytoplasmPostsynaptic Density |
| Alternative Peptide Names | Iq Motif And Sec7 Domain-Containing Protein 3 proteinIQSEC3 proteinKIAA1110 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
