• Human ZP2 (Zona Pellucida Glycoprotein 2, Sperm Receptor) Sandwich ELISA Kit (STJE0013148)

Human ZP2 (Zona Pellucida Glycoprotein 2, Sperm Receptor) Sandwich ELISA Kit (STJE0013148)

SKU:
STJE0013148

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.058ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This ZP2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: ZP2
Gene ID: 7783
Uniprot ID: ZP2_HUMAN
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Expressed in occytes(at protein level).
Post Translational Modifications Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida. Proteolytically cleaved in the N-terminal part by the metalloendopeptidase ASTL exocytosed from cortical granules after fertilization, yielding a N-terminal peptide of about 30 kDa which remains covalently attached to the C-terminal peptide via disulfide bond(s). This cleavage may play an important role in the post-fertilization block to polyspermy. Additional proteolytically cleavage of the N-terminal peptide of 30 kDa occurs in one-cell and two-cell embryos. N-glycosylated. O-glycosylated.contains sulfate-substituted glycans.
Function Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP2 may act as a secondary sperm receptor.
Protein Name Zona Pellucida Sperm-Binding Protein 2
Zona Pellucida Glycoprotein 2
Zp-2
Zona Pellucida Protein A Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 2
Database Links Reactome: R-HSA-2534343
Cellular Localisation Processed Zona Pellucida Sperm-Binding Protein 2: Zona Pellucida
Cell Membrane
Single-Pass Type I Membrane Protein
Alternative ELISA Names Zona Pellucida Sperm-Binding Protein 2 ELISA kit
Zona Pellucida Glycoprotein 2 ELISA kit
Zp-2 ELISA kit
Zona Pellucida Protein A Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 2 ELISA kit
ZP2 ELISA kit
ZPA ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance