Applications: |
ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.055ng/mL |
Detection Limit: |
0.156-10ng/mL |
Short Description: |
This XDH Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
4.5 hrs |
Gene Symbol: |
XDH |
Gene ID: |
7498 |
Uniprot ID: |
XDH_HUMAN |
Sample Type: |
serum, plasma, breast milk or other biological fluids. |
Tissue Specificity | Detected in milk (at protein level). |
Post Translational Modifications | Subject to partial proteolysis.this alters the enzyme from the dehydrogenase form (D) to the oxidase form (O). Contains sulfhydryl groups that are easily oxidized (in vitro).this alters the enzyme from the dehydrogenase form (D) to the oxidase form (O). |
Function | Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro). |
Protein Name | Xanthine Dehydrogenase/Oxidase Includes - Xanthine DehydrogenaseXd - Xanthine OxidaseXoXanthine OxidoreductaseXor |
Database Links | Reactome: R-HSA-74259Reactome: R-HSA-8851680Reactome: R-HSA-9748787 |
Cellular Localisation | CytoplasmPeroxisomeSecreted |
Alternative ELISA Names | Xanthine Dehydrogenase/Oxidase Includes - Xanthine Dehydrogenase ELISA kitXd - Xanthine Oxidase ELISA kitXo ELISA kitXanthine Oxidoreductase ELISA kitXor ELISA kitXDH ELISA kitXDHA ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance