Applications: |
ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.117ng/mL |
Detection Limit: |
0.312-20ng/mL |
Short Description: |
This WNT10B Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
3 hrs |
Gene Symbol: |
WNT10B |
Gene ID: |
7480 |
Uniprot ID: |
WN10B_HUMAN |
Immunogen Region: |
Ready-To-Use |
Sample Type: |
serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | Detected in most adult tissues. Highest levels were found in heart and skeletal muscle. Low levels are found in brain. |
Post Translational Modifications | Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition. |
Function | Member of the Wnt ligand gene family that encodes for secreted proteins, which activate the Wnt signaling cascade. Specifically activates canonical Wnt/beta-catenin signaling and thus triggers beta-catenin/LEF/TCF-mediated transcriptional programs. Involved in signaling networks controlling stemness, pluripotency and cell fate decisions. Acts in the immune system, mammary gland, adipose tissue, bone and skin. |
Protein Name | Protein Wnt-10bProtein Wnt-12 |
Database Links | Reactome: R-HSA-3238698Reactome: R-HSA-373080Reactome: R-HSA-381340 |
Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
Alternative ELISA Names | Protein Wnt-10b ELISA kitProtein Wnt-12 ELISA kitWNT10B ELISA kitWNT12 ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance