| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
4.7pg/mL |
| Detection Limit: |
15.6-1000pg/mL |
| Short Description: |
This VCC1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
CXCL17 |
| Gene ID: |
284340 |
| Uniprot ID: |
CXL17_HUMAN |
| Sample Type: |
serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
| Tissue Specificity | Detected in trachea, stomach, lung and skeletal muscle. Detected in intestine and in normal and asthmatic lung (at protein level). Breast tumors showed 3- to 24-fold up-regulation. |
| Post Translational Modifications | Likely to undergo an endoproteolytic process to form a four-cysteine-containing mature peptide with a canonical CXC chemokine scaffold after secretion. |
| Function | Chemokine that acts as chemoattractant for monocytes, macrophages and dendritic cells. Plays a role in angiogenesis and possibly in the development of tumors. Acts as an anti-inflammatory in the stomach. May play a role in the innate defense against infections. Activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions. 4-Cys CXCL17: Seems to exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17. |
| Protein Name | C-X-C Motif Chemokine 176-Cys Cxcl17Dendritic Cell And Monocyte Chemokine-Like ProteinDmcVegf Coregulated Chemokine 1 Cleaved Into - 4-Cys Cxcl17 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | C-X-C Motif Chemokine 17 ELISA kit6-Cys Cxcl17 ELISA kitDendritic Cell And Monocyte Chemokine-Like Protein ELISA kitDmc ELISA kitVegf Coregulated Chemokine 1 Cleaved Into - 4-Cys Cxcl17 ELISA kitCXCL17 ELISA kitVCC1 ELISA kitUNQ473 ELISA kitPRO842 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
