• Human TTF1 (Transcription Termination Factor, RNA polymerase I) Sandwich ELISA Kit Ready-To-Use (STJE0019239)

Human TTF1 (Transcription Termination Factor, RNA polymerase I) Sandwich ELISA Kit Ready-To-Use (STJE0019239)

SKU:
STJE0019239

£481.50 - £659.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.055ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This TTF1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: TTF1
Gene ID: 7270
Uniprot ID: TTF1_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity.
Protein Name Transcription Termination Factor 1
Ttf-1
Rna Polymerase I Termination Factor
Transcription Termination Factor I
Ttf-I
Database Links Reactome: R-HSA-427389
Reactome: R-HSA-427413
Reactome: R-HSA-5683826
Reactome: R-HSA-73762
Reactome: R-HSA-73863
Cellular Localisation Nucleus
Nucleolus
Nucleoplasm
May Be Localized To The Nucleolus In An Npm1/B23-Dependent Manner
May Be Displaced From The Nucleolus Into The Nucleoplasm In An Cdkn2a/Arf-Dependent Manner
May Shuttle Back And Forth From Nucleoplasm To Nucleolus
Alternative ELISA Names Transcription Termination Factor 1 ELISA kit
Ttf-1 ELISA kit
Rna Polymerase I Termination Factor ELISA kit
Transcription Termination Factor I ELISA kit
Ttf-I ELISA kit
TTF1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance