| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.055ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This TTF1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
TTF1 |
| Gene ID: |
7270 |
| Uniprot ID: |
TTF1_HUMAN |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity. |
| Protein Name | Transcription Termination Factor 1Ttf-1Rna Polymerase I Termination FactorTranscription Termination Factor ITtf-I |
| Database Links | Reactome: R-HSA-427389Reactome: R-HSA-427413Reactome: R-HSA-5683826Reactome: R-HSA-73762Reactome: R-HSA-73863 |
| Cellular Localisation | NucleusNucleolusNucleoplasmMay Be Localized To The Nucleolus In An Npm1/B23-Dependent MannerMay Be Displaced From The Nucleolus Into The Nucleoplasm In An Cdkn2a/Arf-Dependent MannerMay Shuttle Back And Forth From Nucleoplasm To Nucleolus |
| Alternative ELISA Names | Transcription Termination Factor 1 ELISA kitTtf-1 ELISA kitRna Polymerase I Termination Factor ELISA kitTranscription Termination Factor I ELISA kitTtf-I ELISA kitTTF1 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
