• Human TRIP6 (Thyroid Hormone Receptor Interactor 6) Sandwich ELISA Kit (STJE0012810)

Human TRIP6 (Thyroid Hormone Receptor Interactor 6) Sandwich ELISA Kit (STJE0012810)

SKU:
STJE0012810

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.135ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This TRIP6 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: TRIP6
Gene ID: 7205
Uniprot ID: TRIP6_HUMAN
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Abundantly expressed in kidney, liver and lung. Lower levels in heart, placenta and pancreas. Expressed in colonic epithelial cells. Up-regulated in colonic tumors.
Post Translational Modifications Phosphorylation at Tyr-55 by SRC is required for enhancement of lysophosphatidic acid-induced cell migration. Tyr-55 is dephosphorylated by PTPN13.
Function Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor.
Protein Name Thyroid Receptor-Interacting Protein 6
Tr-Interacting Protein 6
Trip-6
Opa-Interacting Protein 1
Oip-1
Zyxin-Related Protein 1
Zrp-1
Database Links
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Junction
Focal Adhesion
Nucleus
Shuttles Between Nucleus And Cytoplasm
Colocalizes With Actin
Alternative ELISA Names Thyroid Receptor-Interacting Protein 6 ELISA kit
Tr-Interacting Protein 6 ELISA kit
Trip-6 ELISA kit
Opa-Interacting Protein 1 ELISA kit
Oip-1 ELISA kit
Zyxin-Related Protein 1 ELISA kit
Zrp-1 ELISA kit
TRIP6 ELISA kit
OIP1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance