| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.135ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This TRIP6 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
TRIP6 |
| Gene ID: |
7205 |
| Uniprot ID: |
TRIP6_HUMAN |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Abundantly expressed in kidney, liver and lung. Lower levels in heart, placenta and pancreas. Expressed in colonic epithelial cells. Up-regulated in colonic tumors. |
| Post Translational Modifications | Phosphorylation at Tyr-55 by SRC is required for enhancement of lysophosphatidic acid-induced cell migration. Tyr-55 is dephosphorylated by PTPN13. |
| Function | Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor. |
| Protein Name | Thyroid Receptor-Interacting Protein 6Tr-Interacting Protein 6Trip-6Opa-Interacting Protein 1Oip-1Zyxin-Related Protein 1Zrp-1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonCell JunctionFocal AdhesionNucleusShuttles Between Nucleus And CytoplasmColocalizes With Actin |
| Alternative ELISA Names | Thyroid Receptor-Interacting Protein 6 ELISA kitTr-Interacting Protein 6 ELISA kitTrip-6 ELISA kitOpa-Interacting Protein 1 ELISA kitOip-1 ELISA kitZyxin-Related Protein 1 ELISA kitZrp-1 ELISA kitTRIP6 ELISA kitOIP1 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
