• Human TNFSF18/GITR Ligand protein (Recombinant) (N-His & Flag) {Biotin} (STJP002269)
  • Human TNFSF18/GITR Ligand protein (Recombinant) (N-His & Flag) {Biotin} (STJP002269)
  • Human TNFSF18/GITR Ligand protein (Recombinant) (N-His & Flag) {Biotin} (STJP002269)
  • Human TNFSF18/GITR Ligand protein (Recombinant) (N-His & Flag) {Biotin} (STJP002269)

Human TNFSF18/GITR Ligand protein (Recombinant) (N-His & Flag) {Biotin} (STJP002269)

SKU:
STJP002269-100

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Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human TNFSF18/GITR Ligand-N-His & Flag protein was developed from hek293 cells and has a target region of N-His & Flag. For use in research applications.
Conjugation: Biotin
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Endotoxin: Less than 1EU per Mu g by the LAL method.
Gene Symbol: TNFSF18
Gene ID: 8995
Uniprot ID: TNF18_HUMAN
Immunogen Region: Gln50-Ser177
Immunogen: Recombinant Biotinylated Human GITR Ligand/TNFSF18 Trimer Protein (Primary Amine Labeling) is expressed from Expi293 with His tag and flag tag at the N-terminal.;It contains Gln50-Ser177.
Function Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1. Promotes leukocyte adhesion to endothelial cells. Regulates migration of monocytes from the splenic reservoir to sites of inflammation.
Protein Name Tumor Necrosis Factor Ligand Superfamily Member 18
Activation-Inducible Tnf-Related Ligand
Aitrl
Glucocorticoid-Induced Tnf-Related Ligand
Hgitrl
Database Links Reactome: R-HSA-5669034
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Protein Names Tumor Necrosis Factor Ligand Superfamily Member 18 protein
Activation-Inducible Tnf-Related Ligand protein
Aitrl protein
Glucocorticoid-Induced Tnf-Related Ligand protein
Hgitrl protein
TNFSF18 protein
AITRL protein
GITRL protein
TL6 protein
UNQ149 protein
PRO175 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance