| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human TNFSF13/APRIL/CD256 Trimer-N-His & Flag protein was developed from hek293 cells and has a target region of N-His & Flag. For use in research applications. |
| Formulation: |
Lyophilized from a 0.2 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: |
Immobilized Human APRIL at 0.2 Mu g/mL (100 Mu L/well) , dose response curve for Human BCMA with the EC50 of 5.2 ng/mL determined by ELISA. |
| Gene Symbol: |
TNFSF13 |
| Gene ID: |
8741 |
| Uniprot ID: |
TNF13_HUMAN |
| Immunogen Region: |
Lys112-Leu250 Trimer |
| Immunogen: |
Recombinant Human MUC16/CA125 Protein is produced by mammalian expression system. The target protein is expressed with sequence (Lys112-Leu250 Trimer) of human APRIL (Accession #O75888) fused with a 6xHis, Flag tag at the N-terminus. |
| Post Translational Modifications | The precursor is cleaved by furin. |
| Function | Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes. |
| Protein Name | Tumor Necrosis Factor Ligand Superfamily Member 13A Proliferation-Inducing LigandAprilTnf- And Apol-Related Leukocyte Expressed Ligand 2Tall-2Tnf-Related Death Ligand 1Trdl-1Cd Antigen Cd256 |
| Database Links | Reactome: R-HSA-450520Reactome: R-HSA-5669034 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Tumor Necrosis Factor Ligand Superfamily Member 13 proteinA Proliferation-Inducing Ligand proteinApril proteinTnf- And Apol-Related Leukocyte Expressed Ligand 2 proteinTall-2 proteinTnf-Related Death Ligand 1 proteinTrdl-1 proteinCd Antigen Cd256 proteinTNFSF13 proteinAPRIL proteinTALL2 proteinZTNF2 proteinUNQ383 proteinPRO715 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
