Host: |
HEK293 cells |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human TNFRSF10C/TRAIL R3-C-6×His protein was developed from hek293 cells and has a target region of C-6×His. For use in research applications. |
Formulation: |
Lyophilized from a 0.2 Mu m filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
TNFRSF10C |
Gene ID: |
8794 |
Uniprot ID: |
TR10C_HUMAN |
Immunogen Region: |
Ala26-Ala221 |
Immunogen: |
Recombinant Human TNFRSF10C/TRAIL R3 Protein is produced by Human cells expression system. The target protein is expressed with sequence (Ala26-Ala221) of human TNFRSF10C/TRAIL R3 (Accession #O14798) fused with a 6×His tag at the C-terminus. |
Post Translational Modifications | N-glycosylated and O-glycosylated. |
Function | Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand. |
Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 10cAntagonist Decoy Receptor For Trail/Apo-2lDecoy Trail Receptor Without Death DomainDecoy Receptor 1Dcr1Lymphocyte Inhibitor Of TrailTnf-Related Apoptosis-Inducing Ligand Receptor 3Trail Receptor 3Trail-R3Trail Receptor Without An Intracellular DomainCd Antigen Cd263 |
Database Links | Reactome: R-HSA-6803211 |
Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 10c proteinAntagonist Decoy Receptor For Trail/Apo-2l proteinDecoy Trail Receptor Without Death Domain proteinDecoy Receptor 1 proteinDcr1 proteinLymphocyte Inhibitor Of Trail proteinTnf-Related Apoptosis-Inducing Ligand Receptor 3 proteinTrail Receptor 3 proteinTrail-R3 proteinTrail Receptor Without An Intracellular Domain proteinCd Antigen Cd263 proteinTNFRSF10C proteinDCR1 proteinLIT proteinTRAILR3 proteinTRID proteinUNQ321 proteinPRO366 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance