• Human TMPRSS4 (Transmembrane Protease, Serine 4) Sandwich ELISA Kit Ready-To-Use (STJE0019046)

Human TMPRSS4 (Transmembrane Protease, Serine 4) Sandwich ELISA Kit Ready-To-Use (STJE0019046)

SKU:
STJE0019046

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.062ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This TMPRSS4 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: TMPRSS4
Gene ID: 56649
Uniprot ID: TMPS4_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity High levels in pancreatic, gastric, colorectal and ampullary cancer. Very weak expression in normal gastrointestinal and urogenital tract. Coexpressed with ACE2 within mature enterocytes.
Post Translational Modifications Proteolytically processed.probably by an autocatalytic mechanism.
Function Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC. (Microbial infection) In gut epithelial cells, facilitates human coronavirus SARS-CoV-2 infection through, at least, the cleavage of coronavirus spike glycoproteins which activates the glycoprotein for host cell entry.
Protein Name Transmembrane Protease Serine 4
Channel-Activating Protease 2
Caph2
Membrane-Type Serine Protease 2
Mt-Sp2 Cleaved Into - Transmembrane Protease Serine 4 Catalytic Chain
Database Links
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Transmembrane Protease Serine 4 Catalytic Chain: Secreted
Activated By Cleavage And Secreted
Alternative ELISA Names Transmembrane Protease Serine 4 ELISA kit
Channel-Activating Protease 2 ELISA kit
Caph2 ELISA kit
Membrane-Type Serine Protease 2 ELISA kit
Mt-Sp2 Cleaved Into - Transmembrane Protease Serine 4 Catalytic Chain ELISA kit
TMPRSS4 ELISA kit
TMPRSS3 ELISA kit
UNQ776 ELISA kit
PRO1570 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance