Host: |
HEK293 cells |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human TMIGD2/CD28H-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: |
Lyophilized from a 0.2 Mu m filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
TMIGD2 |
Gene ID: |
126259 |
Uniprot ID: |
TMIG2_HUMAN |
Immunogen Region: |
Leu23-Gly150 |
Immunogen: |
Recombinant Human TMIGD2/CD28H Protein is produced by Human cells expression system. The target protein is expressed with sequence (Leu23-Gly150) of human TMIGD2/IGPR1 (Accession #Q96BF3) fused with a 6×His tag at the C-terminus. |
Post Translational Modifications | N-glycosylated. |
Function | Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. |
Protein Name | Transmembrane And Immunoglobulin Domain-Containing Protein 2Cd28 HomologImmunoglobulin And Proline-Rich Receptor 1Igpr-1 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Protein Names | Transmembrane And Immunoglobulin Domain-Containing Protein 2 proteinCd28 Homolog proteinImmunoglobulin And Proline-Rich Receptor 1 proteinIgpr-1 proteinTMIGD2 proteinCD28H proteinIGPR1 proteinUNQ3059 proteinPRO9879 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance