| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.118ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This TAT1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
SLC26A8 |
| Gene ID: |
116369 |
| Uniprot ID: |
S26A8_HUMAN |
| Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Expression observed exclusively in testis, restricted to the meiotic phase of the germ cell. Abundant expression located in the seminiferous tubules, concentrated on the luminal side of the tubuli harboring the spermatocytes and spermatids. |
| Post Translational Modifications | N-glycosylated. |
| Function | Antiporter that mediates the exchange of sulfate and oxalate against chloride ions across a membrane. Stimulates anion transport activity of CFTR. May cooperate with CFTR in the regulation of chloride and bicarbonate ions fluxes required for activation of the ADCY10/PKA pathway during sperm motility and sperm capacitation. May play a role in sperm tail differentiation and motility and hence male fertility. |
| Protein Name | Testis Anion Transporter 1Anion Exchange TransporterSolute Carrier Family 26 Member 8 |
| Database Links | |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinLocated At Both The Annulus And The Equatorial Segment Of The Human Sperm Head |
| Alternative ELISA Names | Testis Anion Transporter 1 ELISA kitAnion Exchange Transporter ELISA kitSolute Carrier Family 26 Member 8 ELISA kitSLC26A8 ELISA kitTAT1 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
