Human SNRNP70 protein (Recombinant) (N-His) (STJP010839)

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STJP010839
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SNRNP70-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SNRNP70
Gene ID: 6625
Uniprot ID: RU17_HUMAN
Immunogen Region: Asp90-Glu221
Immunogen: Homo sapiens (Human)
Function Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. Isoform 3: Truncated isoforms that lack the RRM domain cannot bind U1-snRNA. Isoform 4: Truncated isoforms that lack the RRM domain cannot bind U1-snRNA.
Protein Name U1 Small Nuclear Ribonucleoprotein 70 Kda
U1 Snrnp 70 Kda
U1-70k
Snrnp70
Database Links Reactome: R-HSA-72163
Cellular Localisation Nucleus Speckle
Nucleus
Nucleoplasm
Colocalizes With Scnm1 And Luc7l2 In Nuclear Speckles
Alternative Protein Names U1 Small Nuclear Ribonucleoprotein 70 Kda protein
U1 Snrnp 70 Kda protein
U1-70k protein
Snrnp70 protein
SNRNP70 protein
RNPU1Z protein
RPU1 protein
SNRP70 protein
U1AP1 protein

Information sourced from Uniprot.org

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