| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.055ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This SNAT1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
SLC38A1 |
| Gene ID: |
81539 |
| Uniprot ID: |
S38A1_HUMAN |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Expressed in the cerebral cortex by pyramidal and GABAergic neurons, astrocytes and other non-neuronal cells (at protein level). Expressed in placenta, heart, lung, skeletal muscle, spleen, stomach and testis. Highly expressed in cytotrophoblast cells from term placenta. |
| Post Translational Modifications | N-glycosylation plays an important role in the L-glutamine transport. |
| Function | Symporter that cotransports short-chain neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane. The transport is elctrogenic, pH dependent and driven by the Na(+) electrochemical gradient. Participates in the astroglia-derived glutamine transport into GABAergic interneurons for neurotransmitter GABA de novo synthesis. May also contributes to amino acid transport in placental trophoblasts. Also regulates synaptic plasticity. |
| Protein Name | Sodium-Coupled Neutral Amino Acid Symporter 1Amino Acid Transporter A1N-System Amino Acid Transporter 2Solute Carrier Family 38 Member 1System A Amino Acid Transporter 1System N Amino Acid Transporter 1 |
| Database Links | Reactome: R-HSA-210455Reactome: R-HSA-352230 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinRestricted To The Somatodendritic Compartment Of NeuronsFound In The Cellular Processes Of Neurons In The Developing Brain |
| Alternative ELISA Names | Sodium-Coupled Neutral Amino Acid Symporter 1 ELISA kitAmino Acid Transporter A1 ELISA kitN-System Amino Acid Transporter 2 ELISA kitSolute Carrier Family 38 Member 1 ELISA kitSystem A Amino Acid Transporter 1 ELISA kitSystem N Amino Acid Transporter 1 ELISA kitSLC38A1 ELISA kitATA1 ELISA kitNAT2 ELISA kitSAT1 ELISA kitSNAT1 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
