Host: |
HEK293 cells |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human SELP/P-Selectin/CD62P-C-His & Avi protein was developed from hek293 cells and has a target region of C-His & Avi. For use in research applications. |
Conjugation: |
Biotin |
Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SELP |
Gene ID: |
6403 |
Uniprot ID: |
LYAM3_HUMAN |
Immunogen Region: |
Trp42-Ala771 |
Immunogen: |
Biotinylated Recombinant Human P-Selectin/CD62P Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Trp42-Ala771) of Human P-Selectin/CD62P fused with His tag and Avi tag at the C-terminal. |
Function | Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG. |
Protein Name | P-SelectinCd62 Antigen-Like Family Member PGranule Membrane Protein 140Gmp-140Leukocyte-Endothelial Cell Adhesion Molecule 3Lecam3Platelet Activation Dependent Granule-External Membrane ProteinPadgemCd Antigen Cd62p |
Database Links | Reactome: R-HSA-114608Reactome: R-HSA-202733 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Protein Names | P-Selectin proteinCd62 Antigen-Like Family Member P proteinGranule Membrane Protein 140 proteinGmp-140 proteinLeukocyte-Endothelial Cell Adhesion Molecule 3 proteinLecam3 proteinPlatelet Activation Dependent Granule-External Membrane Protein proteinPadgem proteinCd Antigen Cd62p proteinSELP proteinGMRP proteinGRMP protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance