• Human RPN1 (Ribophorin I) Sandwich ELISA Kit Ready-To-Use (STJE0018329)

Human RPN1 (Ribophorin I) Sandwich ELISA Kit Ready-To-Use (STJE0018329)

SKU:
STJE0018329

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.63ng/mL
Detection Limit: 1.56-100ng/mL
Short Description: This RPN1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: RPN1
Gene ID: 6184
Uniprot ID: RPN1_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Expressed in all tissues tested.
Post Translational Modifications Ufmylated by UFL1 in response to endoplasmic reticulum stress, promoting reticulophagy of endoplasmic reticulum sheets.
Function Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Protein Name Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit 1
Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase 67 Kda Subunit
Ribophorin I
Rpn-I
Ribophorin-1
Database Links Reactome: R-HSA-1799339
Reactome: R-HSA-446203
Reactome: R-HSA-9694548
Cellular Localisation Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Single-Pass Type I Membrane Protein
Melanosome
Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
Alternative ELISA Names Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit 1 ELISA kit
Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase 67 Kda Subunit ELISA kit
Ribophorin I ELISA kit
Rpn-I ELISA kit
Ribophorin-1 ELISA kit
RPN1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance