| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
36pg/mL |
| Detection Limit: |
78.1-5000pg/mL |
| Short Description: |
This PTGDS Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
HPGDS |
| Gene ID: |
27306 |
| Uniprot ID: |
HPGDS_HUMAN |
| Sample Type: |
serum, plasma or other biological fluids. |
| Tissue Specificity | Expressed in a number of megakaryocytic cell lines but not in platelets. Highly expressed in adipose tissue, macrophages and placenta. Also expressed at lower levels in lung, heart, lymph nodes, appendix, bone marrow and fetal liver. |
| Post Translational Modifications | |
| Function | Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide. |
| Protein Name | Hematopoietic Prostaglandin D SynthaseH-PgdsGst Class-SigmaGlutathione S-TransferaseGlutathione-Dependent Pgd SynthaseGlutathione-Requiring Prostaglandin D SynthaseProstaglandin-H2 D-Isomerase |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-2162123 |
| Cellular Localisation | Cytoplasm |
| Alternative ELISA Names | Hematopoietic Prostaglandin D Synthase ELISA kitH-Pgds ELISA kitGst Class-Sigma ELISA kitGlutathione S-Transferase ELISA kitGlutathione-Dependent Pgd Synthase ELISA kitGlutathione-Requiring Prostaglandin D Synthase ELISA kitProstaglandin-H2 D-Isomerase ELISA kitHPGDS ELISA kitGSTS ELISA kitPGDS ELISA kitPTGDS2 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
