Human PPBP/CXCL7/NAP-2 protein (Recombinant) (N-His) (STJP006555)

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STJP006555
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PPBP/CXCL7/NAP-2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PPBP
Gene ID: 5473
Uniprot ID: CXCL7_HUMAN
Immunogen Region: Ala59-Asp128
Immunogen: Homo sapiens (Human)
Function LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.
Protein Name Platelet Basic Protein
Pbp
C-X-C Motif Chemokine 7
Leukocyte-Derived Growth Factor
Ldgf
Macrophage-Derived Growth Factor
Mdgf
Small-Inducible Cytokine B7 Cleaved Into - Connective Tissue-Activating Peptide Iii
Ctap-Iii
La-Pf4
Low-Affinity Platelet Factor Iv - Tc-2 - Connective Tissue-Activating Peptide Iii(1-81
Ctap-Iii(1-81 - Beta-Thromboglobulin
Beta-Tg - Neutrophil-Activating Peptide 2(74
Nap-2(74 - Neutrophil-Activating Peptide 2(73
Nap-2(73 - Neutrophil-Activating Peptide 2
Nap-2 - Tc-1 - Neutrophil-Activating Peptide 2(1-66
Nap-2(1-66 - Neutrophil-Activating Peptide 2(1-63
Nap-2(1-63
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-380108
Reactome: R-HSA-418594
Reactome: R-HSA-6798695
Cellular Localisation Secreted
Alternative Protein Names Platelet Basic Protein protein
Pbp protein
C-X-C Motif Chemokine 7 protein
Leukocyte-Derived Growth Factor protein
Ldgf protein
Macrophage-Derived Growth Factor protein
Mdgf protein
Small-Inducible Cytokine B7 Cleaved Into - Connective Tissue-Activating Peptide Iii protein
Ctap-Iii protein
La-Pf4 protein
Low-Affinity Platelet Factor Iv - Tc-2 - Connective Tissue-Activating Peptide Iii(1-81 protein
Ctap-Iii(1-81 - Beta-Thromboglobulin protein
Beta-Tg - Neutrophil-Activating Peptide 2(74 protein
Nap-2(74 - Neutrophil-Activating Peptide 2(73 protein
Nap-2(73 - Neutrophil-Activating Peptide 2 protein
Nap-2 - Tc-1 - Neutrophil-Activating Peptide 2(1-66 protein
Nap-2(1-66 - Neutrophil-Activating Peptide 2(1-63 protein
Nap-2(1-63 protein
PPBP protein
CTAP3 protein
CXCL7 protein
SCYB7 protein
TGB1 protein
THBGB1 protein

Information sourced from Uniprot.org

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