Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.049ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This PDIA6 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | PDIA6 |
Gene ID: | 10130 |
Uniprot ID: | PDIA6_HUMAN |
Sample Type: | tissue homogenates or other biological fluids. |
Tissue Specificity | Expressed in platelets (at protein level). |
Post Translational Modifications | |
Function | May function as a chaperone that inhibits aggregation of misfolded proteins. Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling. May also regulate the UPR via the EIF2AK3 UPR sensor. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin. |
Protein Name | Protein Disulfide-Isomerase A6 Endoplasmic Reticulum Protein 5 Er Protein 5 Erp5 Protein Disulfide Isomerase P5 Thioredoxin Domain-Containing Protein 7 |
Database Links | Reactome: R-HSA-381038 Reactome: R-HSA-381426 Reactome: R-HSA-8957275 |
Cellular Localisation | Endoplasmic Reticulum Lumen Cell Membrane Melanosome Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
Alternative ELISA Names | Protein Disulfide-Isomerase A6 ELISA kit Endoplasmic Reticulum Protein 5 ELISA kit Er Protein 5 ELISA kit Erp5 ELISA kit Protein Disulfide Isomerase P5 ELISA kit Thioredoxin Domain-Containing Protein 7 ELISA kit PDIA6 ELISA kit ERP5 ELISA kit P5 ELISA kit TXNDC7 ELISA kit |
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Information sourced from Uniprot.org