| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.049ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This PDIA6 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
PDIA6 |
| Gene ID: |
10130 |
| Uniprot ID: |
PDIA6_HUMAN |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Expressed in platelets (at protein level). |
| Post Translational Modifications | |
| Function | May function as a chaperone that inhibits aggregation of misfolded proteins. Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling. May also regulate the UPR via the EIF2AK3 UPR sensor. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin. |
| Protein Name | Protein Disulfide-Isomerase A6Endoplasmic Reticulum Protein 5Er Protein 5Erp5Protein Disulfide Isomerase P5Thioredoxin Domain-Containing Protein 7 |
| Database Links | Reactome: R-HSA-381038Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Endoplasmic Reticulum LumenCell MembraneMelanosomeIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative ELISA Names | Protein Disulfide-Isomerase A6 ELISA kitEndoplasmic Reticulum Protein 5 ELISA kitEr Protein 5 ELISA kitErp5 ELISA kitProtein Disulfide Isomerase P5 ELISA kitThioredoxin Domain-Containing Protein 7 ELISA kitPDIA6 ELISA kitERP5 ELISA kitP5 ELISA kitTXNDC7 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
