• Human PDE3B (Phosphodiesterase 3B, cGMP Inhibited) Sandwich ELISA Kit (STJE0011344)

Human PDE3B (Phosphodiesterase 3B, cGMP Inhibited) Sandwich ELISA Kit (STJE0011344)

SKU:
STJE0011344

£352.50 - £682.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 26.35pg/mL
Detection Limit: 78.1-5000pg/mL
Short Description: This PDE3B Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: PDE3B
Gene ID: 5140
Uniprot ID: PDE3B_HUMAN
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity Abundant in adipose tissues.
Post Translational Modifications Phosphorylation at Ser-295 mediates insulin-induced activation of PDE3B.
Function Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological process. Regulates angiogenesis by inhibiting the cAMP-dependent guanine nucleotide exchange factor RAPGEF3 and downstream phosphatidylinositol 3-kinase gamma-mediated signaling. Controls cardiac contractility by reducing cAMP concentration in cardiocytes.
Protein Name Cgmp-Inhibited 3' -5'-Cyclic Phosphodiesterase 3b
Cgipde1
Cgip1
Cyclic Gmp-Inhibited Phosphodiesterase B
Cgi-Pde B
Database Links Reactome: R-HSA-165160
Reactome: R-HSA-418555
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative ELISA Names Cgmp-Inhibited 3' -5'-Cyclic Phosphodiesterase 3b ELISA kit
Cgipde1 ELISA kit
Cgip1 ELISA kit
Cyclic Gmp-Inhibited Phosphodiesterase B ELISA kit
Cgi-Pde B ELISA kit
PDE3B ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance