| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.054ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This PCSK5 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
PCSK5 |
| Gene ID: |
5125 |
| Uniprot ID: |
PCSK5_HUMAN |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Expressed in T-lymphocytes. |
| Post Translational Modifications | |
| Function | Serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXXKRR consensus motif. Likely functions in the constitutive and regulated secretory pathways. Plays an essential role in pregnancy establishment by proteolytic activation of a number of important factors such as BMP2, CALD1 and alpha-integrins. |
| Protein Name | Proprotein Convertase Subtilisin/Kexin Type 5Proprotein Convertase 5Pc5Proprotein Convertase 6Pc6Hpc6Subtilisin/Kexin-Like Protease Pc5 |
| Database Links | Reactome: R-HSA-167060Reactome: R-HSA-8963889 |
| Cellular Localisation | Isoform Pc6a: SecretedSecreted Through The Regulated Secretory PathwayIsoform Pc6b: Endomembrane SystemSingle-Pass Type I Membrane ProteinType I Membrane Protein Localized To A Paranuclear Post-Golgi Network Compartment In Communication With Early Endosomes |
| Alternative ELISA Names | Proprotein Convertase Subtilisin/Kexin Type 5 ELISA kitProprotein Convertase 5 ELISA kitPc5 ELISA kitProprotein Convertase 6 ELISA kitPc6 ELISA kitHpc6 ELISA kitSubtilisin/Kexin-Like Protease Pc5 ELISA kitPCSK5 ELISA kitPC5 ELISA kitPC6 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
