• Human PCGF4 (Polycomb Group Ring Finger Protein 4) Sandwich ELISA Kit (STJE0011301)

Human PCGF4 (Polycomb Group Ring Finger Protein 4) Sandwich ELISA Kit (STJE0011301)

SKU:
STJE0011301

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.122ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This PCGF4 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: BMI1
Gene ID: 100532731/648
Uniprot ID: BMI1_HUMAN
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications Monoubiquitinated. May be polyubiquitinated.which does not lead to proteasomal degradation.
Function Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones.it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A. In the PRC1-like complex, regulates the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Protein Name Polycomb Complex Protein Bmi-1
Polycomb Group Ring Finger Protein 4
Ring Finger Protein 51
Database Links Reactome: R-HSA-2559580
Reactome: R-HSA-3108214
Reactome: R-HSA-3899300
Reactome: R-HSA-4551638
Reactome: R-HSA-4570464
Reactome: R-HSA-4655427
Reactome: R-HSA-8939243
Reactome: R-HSA-8943724
Reactome: R-HSA-8953750
Cellular Localisation Nucleus
Cytoplasm
Alternative ELISA Names Polycomb Complex Protein Bmi-1 ELISA kit
Polycomb Group Ring Finger Protein 4 ELISA kit
Ring Finger Protein 51 ELISA kit
BMI1 ELISA kit
PCGF4 ELISA kit
RNF51 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance