Human PBK protein (Recombinant) (N-His) (STJP008017)

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STJP008017
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PBK-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PBK
Gene ID: 55872
Uniprot ID: TOPK_HUMAN
Immunogen Region: Met35-Val322
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated.in a cell-cycle dependent manner at mitosis.
Function Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.
Protein Name Lymphokine-Activated Killer T-Cell-Originated Protein Kinase
Cancer/Testis Antigen 84
Ct84
Mapkk-Like Protein Kinase
Nori-3
Pdz-Binding Kinase
Spermatogenesis-Related Protein Kinase
Spk
T-Lak Cell-Originated Protein Kinase
Alternative Protein Names Lymphokine-Activated Killer T-Cell-Originated Protein Kinase protein
Cancer/Testis Antigen 84 protein
Ct84 protein
Mapkk-Like Protein Kinase protein
Nori-3 protein
Pdz-Binding Kinase protein
Spermatogenesis-Related Protein Kinase protein
Spk protein
T-Lak Cell-Originated Protein Kinase protein
PBK protein
TOPK protein

Information sourced from Uniprot.org

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