• Human NTSR1 (Neurotensin Receptor 1, High Affinity) Sandwich ELISA Kit Ready-To-Use (STJE0017519)

Human NTSR1 (Neurotensin Receptor 1, High Affinity) Sandwich ELISA Kit Ready-To-Use (STJE0017519)

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STJE0017519

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.126ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This NTSR1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: NTSR1
Gene ID: 4923
Uniprot ID: NTR1_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Expressed in prostate (at protein level). Detected in colon and peripheral blood mononuclear cells. Detected at very low levels in brain.
Post Translational Modifications N-glycosylated. Palmitoylated.this is required for normal localization at membrane rafts and normal GNA11-mediated activation of down-stream signaling cascades. The palmitoylation level increases in response to neurotensin treatment.
Function G-protein coupled receptor for the tridecapeptide neurotensin (NTS). Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system. Signaling leads to the activation of downstream MAP kinases and protects cells against apoptosis.
Protein Name Neurotensin Receptor Type 1
Nt-R-1
Ntr1
High-Affinity Levocabastine-Insensitive Neurotensin Receptor
Ntrh
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-416476
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Membrane Raft
Palmitoylation Is Required For Localization At Cav1-Enriched Membrane Rafts
Alternative ELISA Names Neurotensin Receptor Type 1 ELISA kit
Nt-R-1 ELISA kit
Ntr1 ELISA kit
High-Affinity Levocabastine-Insensitive Neurotensin Receptor ELISA kit
Ntrh ELISA kit
NTSR1 ELISA kit
NTRR ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance