| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.108ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This NPSR Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
NPSR1 |
| Gene ID: |
387129 |
| Uniprot ID: |
NPSR1_HUMAN |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Isoform 4 is ubiquitous.it is detected in glandular epithelia of bronchus, stomach, small intestine, colon, uterus, esophagus, spleen, kidney, pancreas, prostate and breast. Isoform 1 is detected in uterus, colon and prostate, and in the smooth muscle cell layer in bronchial and arterial walls (at protein level). Isoform 1 is predominantly expressed in smooth muscle. Isoform 4 is predominantly expressed in epithelial cells. In bronchial biopsies, it is expressed in smooth muscle cells of asthma patients, but not in control patients.whereas in epithelial cells, its expression is consistently stronger in asthma patients. |
| Post Translational Modifications | |
| Function | G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE-mediated diseases. |
| Protein Name | Neuropeptide S ReceptorG-Protein Coupled Receptor 154G-Protein Coupled Receptor Pgr14G-Protein Coupled Receptor For Asthma Susceptibility |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476Reactome: R-HSA-418555 |
| Cellular Localisation | Isoform 1: Cell MembraneMulti-Pass Membrane ProteinIsoform 3: Cell MembraneIsoform 4: Cell MembraneIsoform 2: CytoplasmIsoform 5: CytoplasmIsoform 6: CytoplasmIsoform 7: CytoplasmIsoform 9: Cytoplasm |
| Alternative ELISA Names | Neuropeptide S Receptor ELISA kitG-Protein Coupled Receptor 154 ELISA kitG-Protein Coupled Receptor Pgr14 ELISA kitG-Protein Coupled Receptor For Asthma Susceptibility ELISA kitNPSR1 ELISA kitGPR154 ELISA kitGPRA ELISA kitPGR14 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
