• Human NPSR (Neuropeptide S Receptor) Sandwich ELISA Kit Ready-To-Use (STJE0017432)

Human NPSR (Neuropeptide S Receptor) Sandwich ELISA Kit Ready-To-Use (STJE0017432)

SKU:
STJE0017432

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.108ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This NPSR Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: NPSR1
Gene ID: 387129
Uniprot ID: NPSR1_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Isoform 4 is ubiquitous.it is detected in glandular epithelia of bronchus, stomach, small intestine, colon, uterus, esophagus, spleen, kidney, pancreas, prostate and breast. Isoform 1 is detected in uterus, colon and prostate, and in the smooth muscle cell layer in bronchial and arterial walls (at protein level). Isoform 1 is predominantly expressed in smooth muscle. Isoform 4 is predominantly expressed in epithelial cells. In bronchial biopsies, it is expressed in smooth muscle cells of asthma patients, but not in control patients.whereas in epithelial cells, its expression is consistently stronger in asthma patients.
Post Translational Modifications
Function G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE-mediated diseases.
Protein Name Neuropeptide S Receptor
G-Protein Coupled Receptor 154
G-Protein Coupled Receptor Pgr14
G-Protein Coupled Receptor For Asthma Susceptibility
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-416476
Reactome: R-HSA-418555
Cellular Localisation Isoform 1: Cell Membrane
Multi-Pass Membrane Protein
Isoform 3: Cell Membrane
Isoform 4: Cell Membrane
Isoform 2: Cytoplasm
Isoform 5: Cytoplasm
Isoform 6: Cytoplasm
Isoform 7: Cytoplasm
Isoform 9: Cytoplasm
Alternative ELISA Names Neuropeptide S Receptor ELISA kit
G-Protein Coupled Receptor 154 ELISA kit
G-Protein Coupled Receptor Pgr14 ELISA kit
G-Protein Coupled Receptor For Asthma Susceptibility ELISA kit
NPSR1 ELISA kit
GPR154 ELISA kit
GPRA ELISA kit
PGR14 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance