Applications: |
ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.053ng/mL |
Detection Limit: |
0.156-10ng/mL |
Short Description: |
This NOSIP Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
3 hrs |
Gene Symbol: |
NOSIP |
Gene ID: |
51070 |
Uniprot ID: |
NOSIP_HUMAN |
Immunogen Region: |
Ready-To-Use |
Sample Type: |
tissue homogenates or other biological fluids. |
Tissue Specificity | Expressed in heart, brain and lung. Present in endothelial cells (at protein level). |
Post Translational Modifications | |
Function | E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB. Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity. |
Protein Name | Nitric Oxide Synthase-Interacting ProteinE3 Ubiquitin-Protein Ligase NosipRing-Type E3 Ubiquitin Transferase NosipEnos-Interacting Protein |
Database Links | Reactome: R-HSA-203754 |
Cellular Localisation | CytoplasmNucleusTranslocates From Nucleus To Cytoplasm In The G2 Phase Of The Cell Cycle |
Alternative ELISA Names | Nitric Oxide Synthase-Interacting Protein ELISA kitE3 Ubiquitin-Protein Ligase Nosip ELISA kitRing-Type E3 Ubiquitin Transferase Nosip ELISA kitEnos-Interacting Protein ELISA kitNOSIP ELISA kitCGI-25 ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance