• Human NKRF (NFKB Repressing Factor) Sandwich ELISA Kit Ready-To-Use (STJE0017368)

Human NKRF (NFKB Repressing Factor) Sandwich ELISA Kit Ready-To-Use (STJE0017368)

SKU:
STJE0017368

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.126ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This NKRF Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: NKRF
Gene ID: 55922
Uniprot ID: NKRF_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Widely and constitutively expressed. Expressed at lower level in colon, peripheral blood lymphocytes, lung and kidney.
Post Translational Modifications
Function Enhances the ATPase activity of DHX15 by acting like a brace that tethers mobile sections of DHX15 together, stabilizing a functional conformation with high RNA affinity of DHX15. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription. May also act as a DNA-binding transcription regulator: interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes.
Protein Name Nf-Kappa-B-Repressing Factor
Nfkb-Repressing Factor
Nrf
Protein Itba4
Database Links
Cellular Localisation Nucleus
Nucleolus
Alternative ELISA Names Nf-Kappa-B-Repressing Factor ELISA kit
Nfkb-Repressing Factor ELISA kit
Nrf ELISA kit
Protein Itba4 ELISA kit
NKRF ELISA kit
ITBA4 ELISA kit
NRF ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance