| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
25.5pg/mL |
| Detection Limit: |
78.1-5000pg/mL |
| Short Description: |
This MGST2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
MGST2 |
| Gene ID: |
4258 |
| Uniprot ID: |
MGST2_HUMAN |
| Sample Type: |
serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
| Tissue Specificity | Liver, spleen, skeletal muscle, heart, adrenals, pancreas, prostate, testis, fetal liver, and fetal spleen. Very low expression in lung, brain, placenta and bone marrow. Abundantly expressed in human umbilical vein endothelial cells (at protein level). |
| Post Translational Modifications | |
| Function | Catalyzes several different glutathione-dependent reactions. Catalyzes the glutathione-dependent reduction of lipid hydroperoxides, such as 5-HPETE. Has glutathione transferase activity, toward xenobiotic electrophiles, such as 1-chloro-2, 4-dinitrobenzene (CDNB). Catalyzes also the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4 (LTC4). Involved in oxidative DNA damage induced by ER stress and anticancer agents by activating LTC4 biosynthetic machinery in nonimmune cells. |
| Protein Name | Microsomal Glutathione S-Transferase 2Microsomal Gst-2Glutathione Peroxidase Mgst2Leukotriene C4 Synthase Mgst2Microsomal Glutathione S-Transferase IiMicrosomal Gst-Ii |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-5423646 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinMicrosome Membrane |
| Alternative ELISA Names | Microsomal Glutathione S-Transferase 2 ELISA kitMicrosomal Gst-2 ELISA kitGlutathione Peroxidase Mgst2 ELISA kitLeukotriene C4 Synthase Mgst2 ELISA kitMicrosomal Glutathione S-Transferase Ii ELISA kitMicrosomal Gst-Ii ELISA kitMGST2 ELISA kitGST2 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
