• Human MGST2 (Microsomal Glutathione S Transferase 2) Sandwich ELISA Kit (STJE0010581)

Human MGST2 (Microsomal Glutathione S Transferase 2) Sandwich ELISA Kit (STJE0010581)

SKU:
STJE0010581

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 25.5pg/mL
Detection Limit: 78.1-5000pg/mL
Short Description: This MGST2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: MGST2
Gene ID: 4258
Uniprot ID: MGST2_HUMAN
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity Liver, spleen, skeletal muscle, heart, adrenals, pancreas, prostate, testis, fetal liver, and fetal spleen. Very low expression in lung, brain, placenta and bone marrow. Abundantly expressed in human umbilical vein endothelial cells (at protein level).
Post Translational Modifications
Function Catalyzes several different glutathione-dependent reactions. Catalyzes the glutathione-dependent reduction of lipid hydroperoxides, such as 5-HPETE. Has glutathione transferase activity, toward xenobiotic electrophiles, such as 1-chloro-2, 4-dinitrobenzene (CDNB). Catalyzes also the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4 (LTC4). Involved in oxidative DNA damage induced by ER stress and anticancer agents by activating LTC4 biosynthetic machinery in nonimmune cells.
Protein Name Microsomal Glutathione S-Transferase 2
Microsomal Gst-2
Glutathione Peroxidase Mgst2
Leukotriene C4 Synthase Mgst2
Microsomal Glutathione S-Transferase Ii
Microsomal Gst-Ii
Database Links Reactome: R-HSA-156590
Reactome: R-HSA-5423646
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Microsome Membrane
Alternative ELISA Names Microsomal Glutathione S-Transferase 2 ELISA kit
Microsomal Gst-2 ELISA kit
Glutathione Peroxidase Mgst2 ELISA kit
Leukotriene C4 Synthase Mgst2 ELISA kit
Microsomal Glutathione S-Transferase Ii ELISA kit
Microsomal Gst-Ii ELISA kit
MGST2 ELISA kit
GST2 ELISA kit
output

Information sourced from Uniprot.org

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